I believe that there's no Anti Virus that's full proof, that's why I have decided to install the following to prevent my computer from all forms of harm:
ANTI VIRUS + ANTI EXECUTABLE + INSTANT SYSTEM RESTORE
The Anti Virus will serve as the first line of defense. The Anti Executable will prevent "*exe" from executing. And if those 2 fails, the Instant System Restore will remove everything after shutting down or restarting your computer.
I hope this help.