Re: Kushina and mito
not a chance
1. their age is too far from eachother
2. Kushina came from Uzushiogakure, Mito lived in Konoha for most of her life.
3. We saw Kushina and Mito together when she came to the village, she was very young, and Mito told that she was gonna have the 9 tailed, because she was too old and soon would die, Kushina was like 6-9 years old. so it is impossible, you can't even have children in the age Mito was in.. This scene can be found in the manga, but I'm too borred, it's probably the chapter where kushina meets naruto.
PS: Look at Tsunades age, and she is Mitos granddaughter. She is like 10 years older than Kushina..