Re: Fifth Hokage
Tsunade had her breakthrough when she became the fifth hokage in the finding tsunade arc.
I don't think she will die, as said above she might just wake up and just live the old way.
But as shes not the most happy person at times, and can easily get offended and go mentally insane, and that she hates danzo. Consider the situasion, she might wake up and recover, and release a insane rage over danzo etc or something.
But i can't see anything that might kill her right now, just the coma.
Would be great if she had a fight breaktrought after the coma tho. She didnt do much at the pain attacks, she just healed, and its the super human strength thats cool about her.