I think Naruto is going to kill Sakura.
See that picture? Alot of things about Team Minato are similar about Team Kakashi. A hero, an Uchiha, and a girl who has strength but isn't as great as the two boys. Whenever Sasuke finally decides to attack Konoha, I think that Naruto will have a situation where he has to kill Sakura.
What Itachi told Naruto in the forest when he gave him the crow seems to me like foreshadowing, letting us know that Naruto will indeed be faced with a horrible decision, and I feel that it's gonna be killing Sakura.
Kakashi had to kill Rin as Obito watched and Sasuke will have to witness Naruto kill Sakura. Granted, Sasuke tried to kill her too, but he was stopped. I think maybe Sasuke will see her dead body and go on a rampage, finally coming to terms with his love for her.
If it doesn't happen, so be it, but it would sure make for an awesome twist/tearjerker!