I think the Sasuke vs Killer Bee fight may have been Kishi's way to give the curse mark to Sasuke because:
Karin says a enzyme in Jugo's blood is what causes his ability the curse mark to activate.
Jugo gave Sasuke his flesh to repair Sasuke’s chest from Killer Bee’s attack which means Sasuke has Jugo’s blood.
Sasuke has Jugo's enzyme which contains the curse marks power (since he has Jugo's blood) but he needs to find a way to activate this enzyme to use the curse mark.
Jugo knows how to use the curse mark without Oro's curse seal so he may be able to teach Sasuke how to activate the enzyme inside him to use the curse mark.
if Kabuto was still around he could give Sasuke a way to activate Jugo's enzyme since he has a lot of Oro's knowledge.
Do you think there's a chance Sasuke could get the curse mark to activate or will Jugo's enzyme stay not active in Sasuke forever? :shrug: